L 5 MTHFR 120c
High dose, 1000 mcg methylated folate, as the all natural 6S isomer.
L-5-MTHF was designed for patients with demonstrated increased need for folate
such as those with either the A1298C or C677T MTHFR mutation. L-5-MTHF (the "L"
signifying that it is the all-natural [6S] isomer) is the active circulating form
of folate found in the body and one of the several forms found in food. In nature
it is found only as this [6S] isomer, which is why DFH provides 5-MTHF as this natural isomer rather than the mixed (or racemic) form. L-5-MTHF should be used when high doses of folate are needed.
Individuals who have tested homozygous with either the A1298C or C677T MTHFR
mutation, or those with elevated homocysteine levels, should be using L-5-MTHF as
the preferred form of folate supplementation. This will be more effective for them
than other forms of folic acid or folates.
Others who may benefit from L-5-MTHF:
-pregnant women and women wishing to become pregnant who have familial history of depression, high homocysteine levels, or genetic defect in MTHFR.
-women with abnormal pap smears (precancerous)
-those with very high homocysteine levels not responding quickly to Homocysteine
Supreme(consider using them together)
-organic acid testing that reveals elevated FIGLU (marker used to identify folate deficiency)
-patients with family history of dementia/vascular dementia
-patients with depression
-long-term use of oral contraceptives, and
-persistent use of medications to lower folate levels, including high doses of NSAIDs
such as aspirin or ibuprofen; anticonvulsants (phenytoin, phenobarbital, and primidone); trimethoprim (antibiotic), pyrimethamine (antimalarial), triamterene (blood pressure med.) and sulfasalazine (treatment for ulcerative colitis).
Serving Size: 2 capsules
Servings Per Container: 90
Amount Per Serving:
Folate ... 1000mcg
Other Ingredients: Microcrystalline cellulose,
spinach juice powder, L-leucine.
Does not contain Gluten.